RISE is brought to you by the makers of Rituxan^® (rituximab).

To learn about Rituxan, visit www.Rituxan.com.

WHAT IS RITUXAN?

Rituxan is a prescription medicine used in adults with another medicine called methotrexate to reduce the signs and symptoms of moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a tumor necrosis factor (TNF) antagonist has been used and did not work well.

People with serious infections should not receive Rituxan.

IMPORTANT SAFETY INFORMATION

Rituxan has been associated with infusion reactions, tumor lysis syndrome, severe skin reactions, and serious infections, including progressive multifocal leukoencephalopathy (PML). Common side effects include infections and infusion reactions.

For more information, please see full Prescribing Information, including Medication Guide.