|
|
|
anti-TNFs (or TNF inhibitors)
A class of biologic DMARDs that targets TNF, one of the chemical messengers involved in RA (eg, adalimumab, etanercept, infliximab).
B-cell
A type of white blood cell that is made in the bone marrow, where it matures through different stages into a plasma cell. Plasma cells are involved in fighting infections by producing antibodies that bring about an immune response. Mature B-cells are found within the blood, lymph, and connective tissue.
targeted B-cell therapy
A treatment that selectively reduces the number of specific B-cells in the blood (eg, Rituximab).
biologic
A treatment made from proteins produced in living cells.
disease-modifying antirheumatic drugs (DMARDs)
A category of drugs used in RA to slow down the development of the disease (eg, methotrexate, leflunomide, hydroxychloroquine sulfate).
flare
A term used to describe times when RA is at its worst.
inflammation
The reaction of body tissues to injury such as irritation in the lining of the joints. Inflammation is characterized by pain, heat, redness, swelling, and loss of function.
rheumatoid arthritis (RA)
A chronic disease that occurs when the immune system attacks the body's joints and other tissues in the body.
rheumatologist
A physician who pursues additional training after medical school and specializes in the diagnosis, treatment, and prevention of arthritis and other rheumatic disorders.
side effect
An unwanted and potentially harmful effect of a drug.
symptom
A sign or an indication of a disorder or disease, especially when experienced by an individual as a change from normal function, sensation, or appearance.
tumor necrosis factor (TNF)
A chemical messenger of the immune system that is involved in RA.
white blood cell
A nearly colorless or "white" cell of the immune system that circulates mainly in the blood and lymph and participates in reactions to invading micro-organisms or foreign particles.
|
|
|
|
|
|
